Search results for: Christoph Lipps

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article

Mesenteric lymph node stromal cell‐derived extracellular vesicles contribute to peripheral de novo induction of Foxp3⁺ regulatory T cells

Maria Pasztoi, Joern Pezoldt, Michael Beckstette, Christoph Lipps, more

European Journal of Immunology > 47 > 12 > 2142 - 2152

Intestinal regulatory T cells (Tregs) are fundamental in peripheral tolerance toward commensals and food‐borne antigens. Accordingly, gut‐draining mesenteric lymph nodes (mLNs) represent a site of efficient peripheral de novo Treg induction when compared to skin‐draining peripheral LNs (pLNs), and we had recently shown that LN stromal cells substantially contribute to this process. Here, we aimed...

article

Proliferation status defines functional properties of endothelial cells

Christoph Lipps, Muhammad Badar, Milada Butueva, Tatyana Dubich, more

Cellular and Molecular Life Sciences > 2017 > 74 > 7 > 1319-1333

Homeostasis of solid tissue is characterized by a low proliferative activity of differentiated cells while special conditions like tissue damage induce regeneration and proliferation. For some cell types it has been shown that various tissue-specific functions are missing in the proliferating state, raising the possibility that their proliferation is not compatible with a fully differentiated state...

article

N-terminal fragment of cardiac myosin binding protein-C triggers pro-inflammatory responses in vitro

Christoph Lipps, Jenine H. Nguyen, Lukas Pyttel, Thomas L. Lynch, more

Journal of Molecular and Cellular Cardiology > 2016 > 99 > C > 47-56

Myocardial infarction (MI) leads to loss and degradation of contractile cardiac tissue followed by sterile inflammation of the myocardium through activation and recruitment of innate and adaptive cells of the immune system. Recently, it was shown that cardiac myosin binding protein-C (cMyBP-C), a protein of the cardiac sarcomere, is degraded following MI, releasing a predominant N-terminal 40-kDa...

article

Evidence that hepatitis B virus replication in mouse cells is limited by the lack of a host cell dependency factor

Florian A. Lempp, Pascal Mutz, Christoph Lipps, Dagmar Wirth, more

Journal of Hepatology > 2016 > 64 > 3 > 556-564

Hepatitis B virus (HBV) is a major human pathogen restricted to hepatocytes. Expression of the specific receptor human sodium taurocholate cotransporting polypeptide (hNTCP) in mouse hepatocytes renders them susceptible to hepatitis delta virus (HDV), a satellite of HBV; however, HBV remains restricted at an early stage of replication. This study aims at clarifying whether this restriction is caused...

chapter

Influence of environmental conditions on the sensing accuracy of Li-Ion battery management systems with passive charge balancing

Thomas Blank, Christoph Lipps, Woldemar Ott, Peter Hoffmann, more

2015 17th European Conference on Power Electronics and Applications (EPE'15 ECCE-Europe) > 1 - 9

2015 17th European Conference on Power Electronics and Applications (EPE '15 ECCE Europe)

Due to their high storage capacity, low self-discharge rate and long lifetime Lithium-Ion batteries are key elements for the emerging electro-mobility and for stationary “Battery Electrical Storage Systems” (BESS). However, Li-Ion batteries are still very expensive and must be handled very carefully to exploit their features optimally. Hence, “Battery Management Systems” (BMS) have been developed...

article

Hepatitis C Virus Replication in Mouse Cells Is Restricted by IFN-Dependent and -Independent Mechanisms

Ramya Nandakumar, Katja Finsterbusch, Christoph Lipps, Berit Neumann, more

Gastroenterology > 2013 > 145 > 6 > 1414-1423.e1

Current treatment strategies for hepatitis C virus (HCV) infection include pegylated interferon (IFN)-alfa and ribavirin. Approximately 50% of patients control HCV infection after treatment, but the broad range of patients' outcomes and responses to treatment, among all genotypes, indicates a role for host factors. Although the IFN system is important in limiting HCV replication, the virus has evolved...

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Search results for: Christoph Lipps

Mesenteric lymph node stromal cell‐derived extracellular vesicles contribute to peripheral de novo induction of Foxp3+ regulatory T cells

Proliferation status defines functional properties of endothelial cells

N-terminal fragment of cardiac myosin binding protein-C triggers pro-inflammatory responses in vitro

Evidence that hepatitis B virus replication in mouse cells is limited by the lack of a host cell dependency factor

Influence of environmental conditions on the sensing accuracy of Li-Ion battery management systems with passive charge balancing

Hepatitis C Virus Replication in Mouse Cells Is Restricted by IFN-Dependent and -Independent Mechanisms

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Mesenteric lymph node stromal cell‐derived extracellular vesicles contribute to peripheral de novo induction of Foxp3⁺ regulatory T cells