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Low plasma concentrations of active transforming growth factor β (TGF-β) are associated with coronary artery disease although the mechanism causing decreased active TGF-β is uncertain. Plasmin activates TGF-β and therefore increased plasminogen activator inhibitor-1 (PAI-1) may cause decreased active TGF-β concentrations. TGF-β is a hydrophobic protein and we hypothesized that post-prandial lipemia...
Post-prandial hypertriglyceridaemia is associated with ischaemic heart disease although the mechanism linking both is uncertain. To determine if measures of insulin resistance, insulin secretion and post-prandial changes in non esterified fatty acid concentration were associated with post-prandial hypertriglyceridaemia, 57 previously healthy Caucasian men between the ages of 57 and 70 years, underwent...